Yep, what the patient really cares about is not, "What's the chance of bad effects per dose or cycle?" but, "What's the chance of bad effects over the course of this treatment?" That's often glossed over and should not be; everyone deserves full and clear information prior to making decisions, but only highly knowledgeable or highly assertive patients typically get that.
This article raises a good point. Choosing the right basis for risk estimation is very important. Perhaps the Regulators should be even more conscious of this and critically evaluate the statistical estimations of risk.
Yep, what the patient really cares about is not, "What's the chance of bad effects per dose or cycle?" but, "What's the chance of bad effects over the course of this treatment?" That's often glossed over and should not be; everyone deserves full and clear information prior to making decisions, but only highly knowledgeable or highly assertive patients typically get that.
This article raises a good point. Choosing the right basis for risk estimation is very important. Perhaps the Regulators should be even more conscious of this and critically evaluate the statistical estimations of risk.